Anti-Human Coagulation factor III/Tissue factor Reference Antibody (MORAb-066, RUO) (HB058056)

Name: Anti-Human Coagulation factor III/Tissue factor Reference Antibody (MORAb-066, RUO)
Brand: abinScience
SKU: HB058056
Price: 326 USD
Availability: InStock

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Overview

Catalog No.	HB058056
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	IgG
Clone ID	MORAb-066
Expression system	Mammalian cells
Clonality	Monoclonal
Target	Tissue factor, CD142, F3, Thromboplastin, Coagulation factor III, TF
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P13726
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	MORAb-066, MORAb066, MORAb066
Background	Tissue factor (CD142/F3) is a ~33 kDa protein. Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. CD142 is the therapeutic target of tisotumab vedotin (Tivdak).
References	1. Pan Z, et al. Characterization of a novel bispecific antibody targeting tissue factor-positive tumors with T cell engagement. Acta Pharm Sin B. 2022 Apr;12(4):1928-1942. [HB058056]
Note	For research use only. Not suitable for clinical or therapeutic use.