Anti-Human 4-1BB/TNFRSF9/CD137 Reference Antibody (Evunzekibart, RUO) (HC336116)

Name: Anti-Human 4-1BB/TNFRSF9/CD137 Reference Antibody (Evunzekibart, RUO)
Brand: abinScience
SKU: HC336116
Price: 176 USD
Availability: InStock

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SDS

Overview

Catalog No.	HC336116
Description	Evunzekibart (HC336116) is a research-grade recombinant antibody targeting CD137. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Human
Applications	ELISA, Bioactivity: FCM, Functional assay, Research in vivo
Host species	Human
Clonality	Monoclonal
Isotype	IgG4-kappa
Expression system	Mammalian cells
Nature	Recombinant
Tested applications	IF
Target	4-1BB ligand receptor, CD137, CDw137, ILA, T-cell antigen 4-1BB homolog, T-cell antigen ILA, TNFRSF9, Tumor necrosis factor receptor superfamily member 9
Endotoxin level	< 10 EU/mg as determined by LAL method.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q07011
Form	Liquid
Storage buffer	0.01M PBS pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	2639688-77-8
Background	Tumor necrosis factor receptor superfamily member 9 (CD137/4-1BB) is a ~27 kDa protein. Receptor for TNFSF9/4-1BBL. Conveys a signal that enhances CD8(+) T-cell survival, cytotoxicity, and mitochondrial activity, thereby promoting immunity against viruses and tumors (Probable).
Note	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG4 (S228P) Recombinant Isotype Control Antibody (13R4) (HP298207)

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SDS-PAGE

SDS-PAGE for Research Grade Evunzekibart.
Bioactivity

Detects recombinant CD137 (Catalog No: HC336011) in indirect ELISA.
Immunofluorescence

Immunofluorescence staining of HDLM2 with Human monoclonal antibody (20ug/ml, overnight at 4°C), followed by Alexa Fluor-488-conjugated secondary antibody (6.5ug/ml, 50minutes at room temperature). The target protein was detected in the cell membrane.

References

Datasheet

Anti-Human 4-1BB/TNFRSF9/CD137 Reference Antibody (Evunzekibart, RUO).pdf

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Formula

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Recombinant Proteins

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Anti-Human 4-1BB/TNFRSF9/CD137 Reference Antibody (Evunzekibart, RUO) (HC336116)

Overview

Images

References

Datasheet

SDS