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Anti-Human 4-1BB/TNFRSF9/CD137 Reference Antibody (Exlinkibart, RUO) (HC336126)

Anti-Human 4-1BB/TNFRSF9/CD137 Reference Antibody (Exlinkibart, RUO)
Anti-Human 4-1BB/TNFRSF9/CD137 Reference Antibody (Exlinkibart, RUO)
Anti-Human 4-1BB/TNFRSF9/CD137 Reference Antibody (Exlinkibart, RUO)
Anti-Human 4-1BB/TNFRSF9/CD137 Reference Antibody (Exlinkibart, RUO)
Anti-Human 4-1BB/TNFRSF9/CD137 Reference Antibody (Exlinkibart, RUO)
Anti-Human 4-1BB/TNFRSF9/CD137 Reference Antibody (Exlinkibart, RUO)
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Overview
Catalog No.HC336126
Description
Exlinkibart (HC336126) is a research-grade recombinant antibody targeting CD137. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivityHuman
ApplicationsELISA, Bioactivity: FCM, Functional assay, Research in vivo
Host speciesHuman
ClonalityMonoclonal
IsotypeIgG1-kappa
Target 4-1BB ligand receptor, CD137, CDw137, ILA, T-cell antigen 4-1BB homolog, T-cell antigen ILA, TNFRSF9, Tumor necrosis factor receptor superfamily member 9
Endotoxin level < 10 EU/mg
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession Q07011
Form Liquid
Storage buffer 0.01M PBS pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names2642171-64-8
Background

Tumor necrosis factor receptor superfamily member 9 (CD137/4-1BB) is a ~27 kDa protein. Receptor for TNFSF9/4-1BBL. Conveys a signal that enhances CD8(+) T-cell survival, cytotoxicity, and mitochondrial activity, thereby promoting immunity against viruses and tumors (Probable).

Note For research use only. Not suitable for clinical or therapeutic use.
Isotype Control Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)
Images
  • Anti-Human 4-1BB/TNFRSF9/CD137 Reference Antibody (Exlinkibart, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Exlinkibart.

  • Anti-Human 4-1BB/TNFRSF9/CD137 Reference Antibody (Exlinkibart, RUO)

    Bioactivity

    Detects recombinant CD137 (Catalog No: HC336011) in indirect ELISA.

  • Anti-Human 4-1BB/TNFRSF9/CD137 Reference Antibody (Exlinkibart, RUO)

    Immunofluorescence

    Immunofluorescence staining of HDLM2 with Human monoclonal antibody (20ug/ml, overnight at 4°C), followed by Alexa Fluor-488-conjugated secondary antibody (6.5ug/ml, 50minutes at room temperature). The target protein was detected in the cell membrane.

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
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C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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