Anti-Human Nectin-2/CD112 Reference Antibody (Remzistotug, RUO) (HV456016)

Name: Anti-Human Nectin-2/CD112 Reference Antibody (Remzistotug, RUO)
Brand: abinScience
SKU: HV456016
Price: 176 USD
Availability: InStock

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Overview

Catalog No.	HV456016
Description	remzistotug (HV456016) is a research-grade recombinant antibody targeting CD112. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research.
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	IgG1, Kappa
Species	Human
Clonality	Monoclonal
Target	CD112/Nectin-2/PVRL2
Endotoxin level	< 10 EU/mg
Purity	>95% as determined by SDS-PAGE.
Accession	Q92692
Form	Liquid
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	2920425-39-2
Background	Nectin-2 (CD112/PVRL2) is a ~57 kDa protein. Modulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Upon interaction with PVRIG, inhibits T-cell proliferation. These interactions are competitive. 1. Zhu, Y. et al. (2016) The Journal of experimental medicine 213, 167-76. PMID: 26755705 2. Warner, MS. et al. (1998) Virology 246, 179-89. PMID: 9657005
Note	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE for Research Grade remzistotug

References

Datasheet

Anti-Human Nectin-2/CD112 Reference Antibody (Remzistotug, RUO).pdf

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Recombinant Proteins

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Anti-Human Nectin-2/CD112 Reference Antibody (Remzistotug, RUO) (HV456016)

Overview

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References

Datasheet

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