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Anti-Human Coagulation factor III/Tissue factor Reference Antibody (Samatatug, RUO) (HB058076)

Anti-Human Coagulation factor III/Tissue factor Reference Antibody (Samatatug, RUO)
Anti-Human Coagulation factor III/Tissue factor Reference Antibody (Samatatug, RUO)
Anti-Human Coagulation factor III/Tissue factor Reference Antibody (Samatatug, RUO)
Anti-Human Coagulation factor III/Tissue factor Reference Antibody (Samatatug, RUO)
Anti-Human Coagulation factor III/Tissue factor Reference Antibody (Samatatug, RUO)
Anti-Human Coagulation factor III/Tissue factor Reference Antibody (Samatatug, RUO)
Price(USD): $
Spec:
  • 100ug
  • 1mg
Number:
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  • Overview

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  • References

  • Datasheet

  • SDS

Overview
Catalog No.HB058076
Description
Samatatug (HB058076) is a research-grade recombinant antibody targeting CD142. Produced in mammalian cells with native-like glycosylation.
Highlights
  • Research Grade — For PK/PD studies, assay development, and ADA research.
  • Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivityHuman
ApplicationsELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host speciesHuman
IsotypeIgG1-kappa
Expression system Mammalian Cells
Clonality Monoclonal
Target Tissue factor, CD142, F3, Thromboplastin, Coagulation factor III, TF
Endotoxin level Please contact the lab for this information.
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P13726
Form Liquid
Storage buffer 0.01M PBS, pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names2861288-57-3
Background

Tissue factor (CD142/F3) is a ~33 kDa protein. Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. CD142 is the therapeutic target of tisotumab vedotin (Tivdak).

Note For research use only. Not suitable for clinical or therapeutic use.
Images
  • Anti-Human Coagulation factor III/Tissue factor Reference Antibody (Samatatug, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Samatatug.

  • Anti-Human Coagulation factor III/Tissue factor Reference Antibody (Samatatug, RUO)

    Bioactivity

    Detects recombinant CD142 (Catalog No: HB058011) in indirect ELISA.

  • Anti-Human Coagulation factor III/Tissue factor Reference Antibody (Samatatug, RUO)

    Western blot

    Lane 1: recombinant human CD142/F3/TF (Catalog No: HB058012)
    Lane 2: 1*loading buffer

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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