Anti-Human Glycosylated CD133/PROM1 Recombinant Antibody (AC133/1) (HT495023)

Name: Anti-Human Glycosylated CD133/PROM1 Recombinant Antibody (AC133/1)
Brand: abinScience
SKU: HT495023
Price: 126 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HT495023

Species reactivity

Human

Applications

FCM, ICC, IF, IHC, WB

Isotype

scFv-His

Clone ID

AC133/1

Clonality

Monoclonal

Target

Prominin-1, Antigen AC133, Prominin-like protein 1, CD133, PROM1, PROML1, MSTP061

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

O43490

RRID

Anti-Human Glycosylated CD133/PROM1 Antibody (AC133/1) (abinScience Cat# HT495023, RRID:AB_3729293)

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Prominin-1 (Glycosylated CD133) is a ~97 kDa protein. May play a role in cell differentiation, proliferation and apoptosis. Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner.

1. Mak, AB. et al. (2014) Journal of molecular biology 426, 2175-82. PMID: 24556617

2. Takenobu, H. et al. (2011) Oncogene 30, 97-105. PMID: 20818439

Note

For research use only.

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