

| Catalog No. | JN990163 | ||||
|---|---|---|---|---|---|
| Species reactivity | Clostridium tetani | ||||
| Applications | ELISA, Neut | ||||
| Host species | Human | ||||
| Isotype | IgG1, kappa | ||||
| Clone ID | SAA2390 | ||||
| Clonality | Monoclonal | ||||
| Target | Tetanus toxin, EC:3.4.24.68, Tentoxylysin, Tetanus toxin light chain, Tetanus toxin chain L, Tetanus toxin heavy chain, Tetanus toxin chain H, tetX | ||||
| Endotoxin level | <10 EU/mg | ||||
| Purity | >95% as determined by SDS-PAGE. | ||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||
| Accession | P04958 | ||||
| Form | Liquid | ||||
| Storage buffer | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Background | Tetanus toxin (tetX) is a ~150 kDa protein. Tetanus toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that catalyzes the hydrolysis of the '76-Gln-|-Phe-77' bond of synaptobrevin-2. | ||||
| Note | For research use only |

SDS-PAGE for Anti-Clostridium tetani tetX/Tetanus toxin Antibody (SAA2390)




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