Anti-Human CD133/PROM1 Recombinant Antibody (SAA0409), APC (HT495237)

Name: Anti-Human CD133/PROM1 Recombinant Antibody (SAA0409), APC
Brand: abinScience
SKU: HT495237
Price: 290 USD
Availability: InStock

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Overview

Catalog No.	HT495237
Species reactivity	Human
Applications	FCM
Host species	Mouse
Isotype	IgG1, kappa
Clone ID	SAA0409
Conjugation	APC
Clonality	Monoclonal
Target	PROML1, PROM1, Prominin-1, Antigen AC133, CD133, Prominin-like protein 1
Endotoxin level	Please contact with the lab for this information.
Associated products	Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21), APC
Accession	O43490
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Store at 4°C for 12 months. Protect from light. Do not freeze.
Background	Prominin-1 (CD133/PROM1) is a ~97 kDa protein. May play a role in cell differentiation, proliferation and apoptosis. Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner. 1. Mak, AB. et al. (2014) Journal of molecular biology 426, 2175-82. PMID: 24556617 2. Takenobu, H. et al. (2011) Oncogene 30, 97-105. PMID: 20818439
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.