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Anti-Clostridium tetani tetX/Tetanus toxin Reference Antibody (Vecantoxatug, RUO) (JN990036)

Anti-Clostridium tetani tetX/Tetanus toxin Reference Antibody (Vecantoxatug, RUO)
Anti-Clostridium tetani tetX/Tetanus toxin Reference Antibody (Vecantoxatug, RUO)
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  • Overview

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  • Datasheet

  • SDS

Overview
Catalog No.JN990036
Description
vecantoxatug (JN990036) is a research-grade recombinant antibody targeting tetX/Tetanus toxin.
Highlights
  • Research Grade — For PK/PD studies, assay development, and ADA research.
Species reactivityClostridium tetani
ApplicationsELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host speciesHuman
IsotypeIgG1, Kappa
Species Clostridium tetani
Clonality Monoclonal
Target tetX/Tetanus toxin
Purity >95% as determined by SDS-PAGE.
Accession P04958
Form Liquid
Reconstitution Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names2956766-52-0
Background

Tetanus toxin (tetX) is a ~150 kDa protein. Tetanus toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that catalyzes the hydrolysis of the '76-Gln-|-Phe-77' bond of synaptobrevin-2.

Note For research use only. Not suitable for clinical or therapeutic use.
Images
  • Anti-Clostridium tetani tetX/Tetanus toxin Reference Antibody (Vecantoxatug, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade vecantoxatug

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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