Ebola Virus (EBOV) Research Reagents — Antibodies, Recombinant Proteins & ELISA Kits

Glycoprotein (GP/GP1)
GP is the sole surface protein and the primary target for neutralizing antibodies, vaccines, and therapeutics. GP mediates viral attachment via NPC1 receptor in endosomes and drives membrane fusion. abinScience provides the most comprehensive ebolavirus GP reagent panel available, including:
• Biosimilar-grade reference antibodies — sequence-identical to approved/clinical therapeutics: Larcaviximab, Porgaviximab, Atoltivimab, Maftivimab, Odesivimab (Inmazeb/REGN-EB3 components), ZMapp, and Ansuvimab (Ebanga)
• InVivoMAb neutralizing antibodies — for in vivo studies: clones Iv01, 6D8, and cross-reactive SEBOV/ZEBOV clone
• Recombinant GP1 proteins — available for ZEBOV (C-His, C-Fc, N-His), SEBOV (C-His), REBOV (C-His), and TAFV (C-His)
• Polyclonal antibodies — species-specific anti-GP1 pAbs for ZEBOV (VK623014), SEBOV (VK623034), REBOV (VK623044), and TAFV (VK623024)
• Nanobody — anti-ZEBOV GP nanobody SAA2283 (VK623013)

Nucleoprotein (NP)
NP is the most abundant viral protein in infected cells and the primary target for diagnostic antigen detection. abinScience offers NP reagents covering multiple species: recombinant NP antibody clone KZ51 (ZEBOV-specific) and SAA2284 (SEBOV-specific), pan-ebolavirus anti-NP antibody SAA2995 and nanobody SAA3007, InVivoMAb anti-NP (cross-reactive REBOV/SEBOV/TAFV/ZEBOV), and species-specific NP proteins and polyclonal antibodies for SEBOV (VK512022) and REBOV (VK518012).

VP40 (Matrix Protein)
VP40 is the major matrix protein that drives virion assembly and budding, and is the primary determinant of the characteristic filamentous morphology of filoviruses. VP40 is essential for virus-like particle (VLP) production systems. Available: recombinant VP40 proteins for ZEBOV (VK783012), SEBOV (VK783032), REBOV (VK783042); recombinant anti-VP40 mAb DS-0126; and species-specific polyclonal antibodies.

VP35, VP24 & Polymerase L
VP35 is an essential polymerase cofactor and potent IFN antagonist — a prime target for antiviral drug development. VP24 inhibits IFN signaling and is involved in nucleocapsid assembly. L protein is the RNA-dependent RNA polymerase. Available: recombinant VP35 protein (VK661022), anti-VP35 mAb (VK661013), anti-VP35 pAb (VK661014); recombinant VP24 proteins (VK661012, VK095022), anti-VP24 pAb (VK095014); and anti-L protein mAb (VK591013).

What is the difference between your reference antibodies and InVivoMAb antibodies?
Reference antibodies (biosimilar-grade, RUO) are sequence-identical to approved therapeutics (e.g., Inmazeb components) and are intended for use as analytical reference standards in PK, ADA, and bioactivity assays. InVivoMAb antibodies are produced under low-endotoxin, azide-free conditions specifically for in vivo animal studies.

Do you offer pan-ebolavirus cross-reactive antibodies?
Yes. The pan-ebolavirus GP reference antibody (VK623106) reacts with REBOV, SEBOV, TAFV, and ZEBOV. For NP, clone SAA2995 and nanobody SAA3007 are pan-ebolavirus reactive. The InVivoMAb anti-NP (VK518010) also cross-reacts with REBOV/SEBOV/TAFV/ZEBOV.

Can I work with these reagents at BSL-2?
Yes. All abinScience ebolavirus products are recombinant proteins and antibodies — no live or inactivated virus material. Standard BSL-1/BSL-2 laboratory conditions are sufficient.

Explore reagents for related filoviruses:

Ebola (ZEBOV/SEBOV/REBOV/TAFV) ✓ Bundibugyo virus (BDBV) Marburg virus (MARV)